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How aspirin helps women get pregnant

A study conducted by the National Institute of Health concludes that aspirin helps women get pregnant. How is that possible? Well, not just any woman can “benefit” from aspirin intake in this manner. Read more to find out how researchers found it works and to whom it applies.

Aspirin intake helps women with chronic inflmmation conceive, according to this recent study.
Photo: Kyle Tsui via Visualhunt / CC BY-NC-ND

The National Institute of Health subdivision called the Eunice Kennedy Shriver National Institute of Child Health and Human Development wanted to see what was the connection between aspirin intake and pregnancy rate, pregnancy loss rate and inflammation during pregnancy. The conclusions of the study were published in The Journal of Clinical Endocrinology & Metabolism.

The hypothesis of the study was that aspirin, taken in a small dose, can reduce inflammation in women that are affected by it chronically, thus increasing their chance of getting pregnant.

Research on the subject involved a number of 1,228 women with ages ranging from 18 to 40, who didn’t have other health problems and were trying to conceive, without success. They were given 81 milligrams of aspirin over a period of six months before becoming pregnant. Those that conceived earlier that six months, were administered aspirin in the same dosage during the entire 36 weeks of pregnancy. Some of them were given, however, a placebo.

The findings showed that women that had been administered aspirin had 35% more chances of conceiving. The treatment was most beneficial for those that had high CRP levels. CRP is a protein produced in the liver as a result of inflammation in the body. Women with high levels of CRP had more chances of suffering a miscarriage, that is if they got pregnant at all. For them, aspirin worked wonders, raising their chances of giving birth from 44% to 59%.

Women with low CRP did not benefit greatly from the aspirin intake, as lead researcher Lindsey A. Sjaarda, Ph.D, noted. There were no significant differences between aspirin and placebo effects, in these women.